Suppliers and Information for (S)-3-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-1-METHYL-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID (CAS 89396-94-1)

This compound is also known as Imidapril hydrochloride and is used as an angiotensin-converting enzyme (ACE) inhibitor for treating hypertension. It is a prodrug that is metabolized in the liver to its active form, imidaprilat. The bioavailability of imidaprilat is about 42% after oral doses of imidapril. Approximately 40% of an oral dose is excreted in the urine, with the rest in the feces.

Frequently Asked Questions

Q: What is the main use of this compound?

A: This compound, known as Imidapril hydrochloride, is primarily used as an angiotensin-converting enzyme (ACE) inhibitor for treating hypertension (high blood pressure).

Q: How is this compound metabolized in the body?

A: Imidapril is a prodrug that is metabolized in the liver to its active form, imidaprilat. The bioavailability of imidaprilat is about 42% after oral doses of imidapril.

Q: Are there any significant drug interactions to be aware of?

A: Yes, there are several potential drug interactions. Some notable ones include enhanced hypotensive effects with anesthetics, increased risk of renal impairment with NSAIDs, and increased risk of hyperkalaemia with potassium-sparing diuretics. It's important to consult with a healthcare professional for a complete list of interactions.

Q: How is this compound excreted from the body?

A: About 40% of an oral dose is excreted in the urine, while the rest is eliminated in the feces.