Trifluoperazine Dihydrochloride (CAS 440-17-5) Suppliers and Product Information

Trifluoperazine dihydrochloride is a phenothiazine compound with antiadrenergic and antidopaminergic properties. It is used as an antipsychotic and antiemetic agent. The compound acts as a potent dopamine D2 receptor inhibitor and also antagonizes adrenergic receptors, with selectivity for α1 over α2 subtypes.

Frequently Asked Questions

Q: What are the main uses of Trifluoperazine dihydrochloride?

A: Trifluoperazine dihydrochloride is primarily used as an antipsychotic medication for treating schizophrenia and severe anxiety. It is also used as an antiemetic to control nausea and vomiting.

Q: How does Trifluoperazine dihydrochloride work?

A: Trifluoperazine dihydrochloride works by antagonizing dopamine D2 receptors and adrenergic receptors. It also interacts with calmodulin and alters the calcium-binding properties of calsequestrin, which may contribute to its effects.

Q: What are some important properties of Trifluoperazine dihydrochloride?

A: Trifluoperazine dihydrochloride is a white to off-white powder with a molecular weight of 480.42. It is soluble in ethanol and has pKa values of 3.9 and 8.1 at 25°C. Its melting point is between 243-260°C (with decomposition).