Cefadroxil (CAS 66592-87-8) Suppliers and Product Information

Cefadroxil is a semi-synthetic first-generation β-lactam cephalosporin antibiotic. It has a broad spectrum of antimicrobial action against both Gram-positive and Gram-negative microorganisms. It is used to treat various infections including urinary tract infections, skin and skin structure infections, pharyngitis, and tonsillitis caused by susceptible bacteria.

Pharmacokinetics: - Oral absorption: 90% - Plasma half-life: 1-1.5 hours - Plasma protein binding: 20% - Elimination: Primarily unchanged through urine (90% of dose in 24 hours)

Frequently Asked Questions about Cefadroxil

Q: What is the main advantage of Cefadroxil over other similar antibiotics?

A: The main advantage of Cefadroxil is its somewhat prolonged duration of action, which allows for once-daily dosing. This is due to its relatively slow urinary excretion compared to other cephalosporins.

Q: How does Cefadroxil work?

A: Cefadroxil acts as a bactericide by disrupting the process of restoring the membranes of bacteria. It interferes with cell wall synthesis, leading to bacterial cell lysis.

Q: Are there any notable drug interactions with Cefadroxil?

A: Yes, there is a potentially hazardous interaction with anticoagulants. Cefadroxil may enhance the effects of coumarin-type anticoagulants.

Q: Is Cefadroxil used in veterinary medicine?

A: Yes, Cefadroxil is approved for oral therapy in treating susceptible infections of the skin, soft tissue, and genitourinary tract in dogs and cats.