Property | Information |
---|---|
Product Name | Pilsicainide |
CAS Number | 88069-67-4 |
Molecular Formula | C17H24N2O |
Molecular Weight | 272.39 |
Synonyms | N-(2,6-Dimethylphenyl)-2-(1,2,3,6,7-tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide, SUN-1165, Sunrhythm |
Storage | Sealed in dry, 2-8°C |
Use | Class IC antiarrhythmic drug for treatment of ventricular tachycardia |
Pilsicainide is a sodium channel blocker used as an antiarrhythmic drug, particularly for the management of atrial tachyarrhythmias in Japan. It is highly soluble in glacial acetic acid and soluble in methanol, ethanol, or water. The compound has a melting point of 212-214°C and is typically obtained through crystallization from ethanol-diethyl ether.
Q: What is the main use of Pilsicainide?
A: Pilsicainide is primarily used as a class IC antiarrhythmic drug for the treatment of patients with ventricular tachycardia, especially when other antiarrhythmic drugs are ineffective or intolerable. It is particularly effective in managing atrial tachyarrhythmias.
Q: How does Pilsicainide work?
A: Pilsicainide functions by blocking the fast inward movement of sodium ions through the Nav1.5 sodium channel. This action contributes to the rapid depolarization characteristic of phase 0 in the cardiac action potential. It is a pure sodium channel blocker and does not significantly affect other cardiac channels like potassium and calcium channels.
Q: What are the chemical properties of Pilsicainide?
A: Pilsicainide has the molecular formula C17H24N2O and a molecular weight of 272.39 g/mol. It is highly soluble in glacial acetic acid and soluble in methanol, ethanol, or water. The compound has a melting point of 212-214°C.
Company Name | Contact | Product Details |
---|---|---|
Jinan Carbotang Biotech Co Ltd | Tel: 86 15866703830 | Purity: 98%, Package: 5KG, 1KG |
Hubei Jusheng Technology Co Ltd | Tel: 86 18871490254 | Purity: 99%, Package: 5KG, 1KG |
CONIER CHEM AND PHARMA LIMITED | Tel: 86 18523575427 | Purity: 99%, Package: 1kg |
Career Henan Chemical Co | Tel: 86 0371 86658258, 86 13203830695 | Purity: 98% HPLC, Package: 1KG |
Shaanxi Dideu Medichem Co., Ltd | Tel: 86 29 87569265, 86 18612256290 | Purity: 99%, Package: 1g, 10g, 100g, 1KG, 25KG |
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