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Nimetazepam Overview

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  • 2024-08-06 00:08:08
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Uses: Sedative-hypnotic, anticonvulsant, short-term management of insomnia.

2Nimetazepam Overview

Origin: Erimin, Sumitomo, Japan, 1977.

Manufacturing Process: Involves multiple chemical reactions including the use of boron trifluoride etherate and chromic anhydride.

Toxicity: LD50 varies based on administration route, with values of 910 mg/kg (oral) in mice.

Pharmacokinetics: Rapid absorption with effects felt within 15–30 minutes; half-life ranges from 0.5 to 26.5 hours.

Recreational Use: Known for high abuse potential, particularly in Southeast Asia.

Questions and Answers

What is Nimetazepam used for? It is primarily used as a sedative-hypnotic and anticonvulsant for the short-term management of insomnia.

Is Nimetazepam a controlled substance? Yes, it is classified as a Schedule IV controlled substance.

What are the risks associated with Nimetazepam? There is a significant risk of misuse and dependence, particularly among recreational users.

How is Nimetazepam typically administered? It is usually taken orally, with effects felt quickly due to its high bioavailability.

Property Details
Product Name Nimetazepam
CAS Number 2011-67-8
Synonyms 1-methyl-7-nitro-5-phenyl-3H-1,4-benzodiazepin-2-one, Erimin, Methylnitrazepam
Molecular Formula C16H13N3O3
Molecular Weight 295.29 g/mol
Melting Point 156.5 - 157.5 °C
Boiling Point 436.98 °C (approx.)
Density 1.1952 (approx.)
Refractive Index 1.6500 (approx.)
Solubility Slightly soluble in chloroform and methanol
Storage Temperature -20 °C
Hazard Codes F, T
Risk Statements 11, 23, 24, 25, 39
Safety Statements 16, 36, 37, 45
Controlled Substance Schedule IV