Uses: Sedative-hypnotic, anticonvulsant, short-term management of insomnia. Origin: Erimin, Sumitomo, Japan, 1977. Manufacturing Process: Involves multiple chemical reactions including the use of boron trifluoride etherate and chromic anhydride. Toxicity: LD50 varies based on administration route, with values of 910 mg/kg (oral) in mice. Pharmacokinetics: Rapid absorption with effects felt within 15–30 minutes; half-life ranges from 0.5 to 26.5 hours. Recreational Use: Known for high abuse potential, particularly in Southeast Asia. |
What is Nimetazepam used for? It is primarily used as a sedative-hypnotic and anticonvulsant for the short-term management of insomnia.
Is Nimetazepam a controlled substance? Yes, it is classified as a Schedule IV controlled substance.
What are the risks associated with Nimetazepam? There is a significant risk of misuse and dependence, particularly among recreational users.
How is Nimetazepam typically administered? It is usually taken orally, with effects felt quickly due to its high bioavailability.
Property | Details |
---|---|
Product Name | Nimetazepam |
CAS Number | 2011-67-8 |
Synonyms | 1-methyl-7-nitro-5-phenyl-3H-1,4-benzodiazepin-2-one, Erimin, Methylnitrazepam |
Molecular Formula | C16H13N3O3 |
Molecular Weight | 295.29 g/mol |
Melting Point | 156.5 - 157.5 °C |
Boiling Point | 436.98 °C (approx.) |
Density | 1.1952 (approx.) |
Refractive Index | 1.6500 (approx.) |
Solubility | Slightly soluble in chloroform and methanol |
Storage Temperature | -20 °C |
Hazard Codes | F, T |
Risk Statements | 11, 23, 24, 25, 39 |
Safety Statements | 16, 36, 37, 45 |
Controlled Substance | Schedule IV |
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