Sulfamethazine (CAS 57-68-1) Suppliers and Product Information

Sulfamethazine is an antibacterial sulfonamide used in veterinary medicine. It acts by competitively inhibiting dihydropteroate synthase, blocking folate synthesis and inhibiting bacterial growth. The compound is metabolized by cytochrome P450 isoforms and arylamine N-acetyltransferase 2 in a sex-dependent manner.

Frequently Asked Questions about Sulfamethazine

Q: What is the main use of Sulfamethazine?

A: Sulfamethazine is primarily used as an antibacterial agent in veterinary medicine for treating infections caused by susceptible bacteria, including pneumococcal, staphylococcal, and streptococcal infections.

Q: How does Sulfamethazine work?

A: Sulfamethazine works by competitively inhibiting the enzyme dihydropteroate synthase, which is essential for bacterial folate synthesis. This inhibition blocks bacterial growth and multiplication.

Q: What are the potential side effects of Sulfamethazine?

A: While specific side effects are not detailed in the given information, sulfonamides in general can cause serious adverse effects such as renal toxicity, exfoliative dermatitis, erythema multiforme, and blood formation issues like agranulocytosis and hemolytic or aplastic anemia.

Q: Is Sulfamethazine stable?

A: Sulfamethazine is generally stable but is sensitive to light. It may also be sensitive to heat, and the presence of oxygen and moisture may accelerate the effects of heat and light.