Thioridazine Hydrochloride (CAS 130-61-0) Suppliers and Product Information

Thioridazine hydrochloride is a dopamine receptor blocker and first-generation antipsychotic. It has been used as an intercalating agent for ***yzing double-stranded DNA integrity and as a positive control for inhibiting hepatic enzyme cytochrome P4502D6 (CYP2D6) in human liver microsomes. The compound is known to bind strongly to dopamine receptors on cancer stem cells, causing differentiation while leaving normal cells unaffected.

Frequently Asked Questions about Thioridazine Hydrochloride

Q: What are the main uses of Thioridazine Hydrochloride?

A: Thioridazine Hydrochloride is primarily used as an antipsychotic medication. It functions as a dopamine receptor blocker and has been used in the treatment of schizophrenia and other psychotic disorders. Additionally, it has applications in research, particularly in DNA ***ysis and as a control in enzyme inhibition studies.

Q: What are the safety considerations when handling Thioridazine Hydrochloride?

A: Thioridazine Hydrochloride should be handled with care. It is classified as harmful (Xn) and carries risk statements including R22 (harmful if swallowed), R36/37/38 (irritating to eyes, respiratory system, and skin), and R50/53 (very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment). Proper personal protective equipment should be used when handling this compound.

Q: How should Thioridazine Hydrochloride be stored?

A: Thioridazine Hydrochloride should be stored at 2-8°C. It is light-sensitive and hygroscopic, so it should be kept in a tightly sealed container protected from light and moisture. Desiccation at room temperature is recommended for long-term storage.