Estramustine Phosphate (CAS 4891-15-0) Suppliers and Product Information

Estramustine phosphate is a nitrogen mustard linked to estradiol, used to treat prostatic neoplasms. It is an antimicrotubule agent used for advanced metastatic prostate cancer. The compound is a dual cytostatic and hormonal anticancer agent, acting as a prodrug of estramustine, estromustine, and estradiol.

Frequently Asked Questions

Q: What is the main use of estramustine phosphate?

A: Estramustine phosphate is primarily used in the treatment of advanced metastatic prostate cancer.

Q: How is estramustine phosphate administered?

A: It can be taken orally multiple times a day or administered by injection into a vein.

Q: What are the main side effects of estramustine phosphate?

A: Common side effects include nausea, vomiting, gynecomastia, feminization, demasculinization, sexual dysfunction, blood clots, and cardiovascular complications.

Q: How does estramustine phosphate work in the body?

A: Estramustine phosphate is a prodrug that is metabolized in the body to active compounds. It has both cytostatic (chemotherapeutic) effects and estrogenic effects, which contribute to its anticancer activity.