Acemetacin (CAS 53164-05-9) Suppliers and Product Information

Acemetacin is a non-steroidal anti-inflammatory drug used in the treatment of pain and restricted mobility resulting from chronic articular rheumatism, degenerative articular disease, gout, and inflammation of muscles, joints, and tendons. It causes less gastrointestinal blood loss than indomethacin. Its anti-inflammatory activity results from the liberation of the parent compound, indomethacin.

Frequently Asked Questions about Acemetacin

Q: What is the main use of Acemetacin?

A: Acemetacin is primarily used as a non-steroidal anti-inflammatory drug (NSAID) for treating pain and inflammation associated with various conditions such as rheumatoid arthritis, osteoarthritis, and low back pain. It is also used for postoperative pain and inflammation.

Q: How does Acemetacin work?

A: Acemetacin works as a potent inhibitor of COX-2 (cyclooxygenase-2), which is responsible for producing inflammatory mediators. It also biotransforms to indomethacin in the body, which contributes to its ***gesic and anti-inflammatory effects.

Q: What are the physical properties of Acemetacin?

A: Acemetacin is a solid at room temperature, appearing as very fine, pale-yellow crystals. It has a melting point of 149-153°C and is practically insoluble in water but soluble in acetone and slightly soluble in anhydrous ethanol.

Q: How should Acemetacin be stored?

A: Acemetacin should be stored at -20°C in a freezer. It's important to keep it sealed and dry to maintain its stability.