Homatropine Hydrobromide (CAS 51-56-9) Suppliers and Product Information

Homatropine Hydrobromide is an anticholinergic agent used in eye drops as a cycloplegic and mydriatic to dilate the pupil. It acts as an inhibitor of the muscarinic acetylcholine receptors. The compound reduces acetylcholine-induced contractions of isolated goat detrusor muscle strips at a concentration of 5 μM and inhibits acetylcholine- or methacholine-induced contraction of isolated rat anococcygeus muscle at 1 μM.

Frequently Asked Questions about Homatropine Hydrobromide

Q: What is the main use of Homatropine Hydrobromide?

A: Homatropine Hydrobromide is primarily used in ophthalmology as a cycloplegic and mydriatic agent. It is used in eye drops to dilate the pupil and paralyze the ciliary structure of the eye.

Q: How does Homatropine Hydrobromide compare to Atropine?

A: Homatropine Hydrobromide behaves similarly to atropine but is weaker and less toxic. In the eye, it acts more rapidly but less persistently than atropine. Pupil dilation occurs in about 15 to 20 minutes, and the action subsides in about 24 hours.

Q: What are the storage requirements for Homatropine Hydrobromide?

A: Homatropine Hydrobromide should be stored at a temperature between 2-8°C. It is affected by light, so proper storage conditions are important to maintain its stability.

Q: Is Homatropine Hydrobromide soluble in water?

A: Yes, Homatropine Hydrobromide is freely soluble in water. It is also sparingly soluble in alcohol.