Cefprozil (CAS 92665-29-7) Suppliers and Product Information

Cefprozil is a second-generation cephalosporin antibiotic used to treat various bacterial infections. It has broad-spectrum antibacterial activity and is particularly effective against streptococci, Neisseria spp., and S. aureus. It is also active against certain Enterobacteriaceae family members.

Cefprozil is orally active with excellent absorption (oral bioavailability about 95%) and is not affected by antacids or histamine H2 antagonists. It has a plasma half-life of 1.2 to 1.4 hours, allowing for twice-daily dosing in most cases.

Frequently Asked Questions about Cefprozil

What is Cefprozil used for?

Cefprozil is used to treat various bacterial infections, including bronchitis, ear infections, skin infections, and other bacterial infections. It is particularly effective against respiratory and urinary tract infections caused by susceptible organisms.

How is Cefprozil administered?

Cefprozil is administered orally. Its absorption is not affected by food or antacids, and there is no accumulation on multiple dosing regimens.

What are the common side effects of Cefprozil?

Common side effects include nausea, vomiting, and abdominal discomfort. Diarrhea and gastrointestinal discomfort may also occur. Rare side effects can include pseudomembranous colitis, serum sickness-like reactions, and very rare neurological disturbances.

How does Cefprozil compare to other cephalosporins?

Cefprozil's spectrum of antibacterial activity is comparable to cefaclor but exhibits greater activity against certain bacteria such as S. aureus, S. epidermidis, and H. influenzae. It is more active than first-generation cephalosporins against some Enterobacteriaceae family members.

Is Cefprozil effective against H. influenzae?

While Cefprozil has some activity against H. influenzae, it is not recommended for use in infections where H. influenzae is or is likely to be implicated.