Estradiol (CAS 57-91-0) Suppliers and Product Information

17α-Estradiol is an endogenous estrogen receptor ligand with Ki values of 0.2 nM for ERα and 1.2 nM for ERβ receptors. It has biological activity in human breast cancer cells and may have implications for hormone replacement therapy and treatment of neurodegenerative disorders.

Frequently Asked Questions

Q: What is the difference between 17α-Estradiol and 17β-Estradiol?

A: 17α-Estradiol and 17β-Estradiol are stereoisomers that differ in the orientation of the hydroxyl group at the 17 position. 17β-Estradiol is the more common and potent form found naturally in humans, while 17α-Estradiol has lower estrogenic activity but may have neuroprotective properties.

Q: What are some applications of 17α-Estradiol?

A: 17α-Estradiol is used in research related to estrogen receptors, breast cancer, and neurodegenerative disorders. It may have potential applications in hormone replacement therapy and treatment of conditions like Alzheimer's disease and ischemic stroke.