Flurithromycin (CAS 82664-20-8) Suppliers and Product Information

Flurithromycin is a semisynthetic derivative of erythromycin A, with a fluorine atom at the C-8 position of the erythronolide A ring. It is an orally active broad-spectrum antibiotic with improved acid stability compared to erythromycin. Flurithromycin is active against various bacterial strains, including streptococci, Moraxella catarrhalis, Neisseria gonorrhoeae, and Chlamydia trachomatis.

The compound has been used in research and as a pharmaceutical agent for treating lower respiratory tract infections. It is generally well-tolerated and demonstrates pharmacokinetic properties suitable for oral administration.

Frequently Asked Questions about Flurithromycin

Q: What is the main advantage of Flurithromycin over Erythromycin?

A: Flurithromycin has improved acid stability compared to erythromycin due to the presence of a fluorine atom at the C-8 position of the erythronolide A ring. This modification enhances its oral bioavailability and effectiveness.

Q: What are the main applications of Flurithromycin?

A: Flurithromycin has been used primarily as an antibacterial agent for treating lower respiratory tract infections. It is effective against various bacterial strains, including streptococci, Moraxella catarrhalis, and Chlamydia trachomatis.

Q: How is Flurithromycin typically administered?

A: Flurithromycin is typically administered orally. In clinical studies, it has been given as a single 500 mg dose or as 500 mg every 8 hours for multiple doses.