Property | Information |
---|---|
Product Name | Benzhexol hydrochloride |
CAS Number | 52-49-3 |
Molecular Formula | C20H31NO·HCl |
Molecular Weight | 337.93 |
EINECS | 200-142-5 |
Appearance | White solid |
Melting Point | 114.3-115.0°C (free base) |
Water Solubility | 670.9 μg/L (22.5-186°C) |
Storage | Room temperature, inert atmosphere |
Benzhexol hydrochloride, also known as Trihexyphenidyl hydrochloride, is an anticholinergic medication used primarily in the treatment of Parkinson's disease and to manage extrapyramidal side effects of antipsychotic drugs. It acts as an antagonist of M1 muscarinic acetylcholine receptors, with selective binding to rat M1 receptors in the cerebral cortex over M2 receptors in heart tissue.
Q: What are the main uses of Benzhexol hydrochloride?
A: Benzhexol hydrochloride is primarily used in the treatment of Parkinson's disease and to manage extrapyramidal side effects caused by antipsychotic medications. It is also used to treat certain types of tremors and muscle stiffness.
Q: What are the common side effects of Benzhexol hydrochloride?
A: Common side effects include drowsiness, dizziness, constipation, flushing, nausea, nervousness, blurred vision, and dry mouth. More severe side effects may include difficulty urinating, chest pain, irregular heartbeat, and mental/mood changes.
Q: How does Benzhexol hydrochloride work?
A: Benzhexol hydrochloride works as an anticholinergic agent, specifically as an antagonist of M1 muscarinic acetylcholine receptors. This action helps to reduce the imbalance between dopamine and acetylcholine in the brain, which is associated with Parkinson's disease symptoms.
Q: Is Benzhexol hydrochloride safe for long-term use?
A: While Benzhexol hydrochloride can be used long-term under medical supervision, it's important to regularly assess its benefits and potential side effects. Long-term use may lead to tolerance and potential cognitive side effects, especially in older ***s.
Company Name | Contact | Product Details |
---|---|---|
Shandong Perfect Biotechnology Co Ltd | Tel: 86 53169958659, 8618596095638 | Purity: 98% (HPLC), Package: 1KG, 5KG, 25KG |
Hebei Yanxi Chemical Co Ltd | Tel: 86 17531190177, 8617531190177 | Purity: 99%, Package: 1kg (40USD) |
Nantong Guangyuan Chemical Co Ltd | Tel: 17712220823 | Purity: 99%, Package: 1kg (10USD) |
Henan Tianfu Chemical Co Ltd | Tel: 86 0371 55170693, 86 19937530512 | Purity: 99%, Package: 25KG, 5KG, 1KG |
Career Henan Chemical Co | Tel: 86 0371 86658258, 8613203830695 | Purity: 98%, Package: 1KG (1USD) |
This article was written by bob and published on 2024-07-23 04:07:53. Original article, reproduction is prohibited. The content is for entertainment purposes only and should not be taken as fact.
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