Gatifloxacin Suppliers and Product Information

Gatifloxacin is a quinolone antibiotic used to treat acute sinus, lung, or urinary tract infections and sexually transmitted bacterial infections. It inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication and cell division. Gatifloxacin is available in oral tablet form or by injection and is known for its enhanced activity against Gram-positive, atypical agents, and some anaerobes, as well as broad-spectrum activity against Gram-negative bacteria.

Frequently Asked Questions about Gatifloxacin

Q: What is the standard dose of Gatifloxacin?

A: The standard dose of Gatifloxacin is 400 mg once daily. Both oral and intravenous formulations are available.

Q: What are the common side effects of Gatifloxacin?

A: Common side effects of Gatifloxacin include nausea, vaginitis (irritation or inflammation of the vagina), diarrhea, headache, dizziness, and irregular heartbeats. For ophthalmic use, side effects may include eye irritation, eye pain, and changes in taste.

Q: How does Gatifloxacin compare to other antibiotics in treating recurrent otitis media?

A: In a study comparing Gatifloxacin with amoxicillin-clavulanate for treating recurrent otitis media and acute otitis media in children, Gatifloxacin once daily was found to be as effective as amoxicillin-clavulanate twice daily. Both drugs were well-tolerated, with diarrhea being the most common side effect.

Q: Is Gatifloxacin still widely used?

A: Gatifloxacin has been withdrawn in most countries for systemic usage due to concerns about QTc interval prolongation and interference with diabetes mellitus. However, it remains in use in North America as an ophthalmic solution.