Azatadine Maleate (200 MG) CAS 3978-86-7: Suppliers and Product Information

Azatadine maleate is an antihistamine with anticholinergic and antiserotonergic activities. It is a histamine H1 receptor antagonist with a Ki value of 3.9 nM. This compound is used to treat symptoms of allergies and the common cold, such as sneezing, runny nose, itching, watery eyes, and hives. Azatadine maleate is classified as an anti-allergic agent.

The compound was originally developed by Idulian/Unilabo in France in 1968. It is also known by brand names such as Optimine and Zadine. Azatadine maleate is a potent, long-acting antihistamine that has shown greater potency than chlorpheniramine in early testing, exhibiting more than three times the potency in isolated guinea pig ileum screens and more than seven times the oral potency in protecting guinea pigs against histamine-induced lethality.

Frequently Asked Questions about Azatadine Maleate

Q: What is the primary use of Azatadine Maleate?

A: Azatadine Maleate is primarily used as an antihistamine to treat symptoms of allergies and the common cold, such as sneezing, runny nose, itching, watery eyes, and hives.

Q: What is the recommended storage condition for Azatadine Maleate?

A: Azatadine Maleate should be stored sealed in a dry place at room temperature.

Q: Is Azatadine Maleate soluble in water?

A: The solubility of azatadine maleate in PBS (pH 7.2) is approximately 10 mg/ml. It is slightly soluble in DMSO and methanol.

Q: What is the purity of commercially available Azatadine Maleate?

A: Most suppliers offer Azatadine Maleate with a purity of ≥99%.