Property | Value |
---|---|
Product Name | Isocarboxazid |
CAS Number | 59-63-2 |
Molecular Formula | C12H13N3O2 |
Molecular Weight | 231.25 |
EINECS | 200-438-4 |
Melting Point | 98-100°C |
Boiling Point | 373.33°C (rough estimate) |
Density | 1.206 |
Refractive Index | 1.5290 (estimate) |
Storage Temperature | -20°C Freezer |
Solubility | Slightly soluble in acetonitrile and chloroform |
Form | Solid |
Color | White to off-white |
Water Solubility | 0.8g/L (25°, 186°C) |
Isocarboxazid is a powerful monoamine oxidase inhibitor (MAOI) used as an antidepressant. It was introduced in 1959 for the treatment of depressive illness. The compound is used for depressions that do not respond to other drugs. It's important to note that MAOIs have potential serious interactions with foods containing tyramine, which has led to restrictive regulatory actions. However, isocarboxazid remains available in several countries and is considered a relatively safe example of this class of compounds.
Q: What is the main use of Isocarboxazid?
A: Isocarboxazid is primarily used as an antidepressant, specifically for treating depressions that do not respond to other medications. It is a monoamine oxidase inhibitor (MAOI).
Q: Are there any special precautions when using Isocarboxazid?
A: Yes, as with other MAOIs, there are potential serious interactions between Isocarboxazid and foods containing tyramine. Patients taking this medication need to follow dietary restrictions and should be monitored closely by their healthcare provider.
Q: How is Isocarboxazid synthesized?
A: Isocarboxazid can be synthesized from acetylacetone through a series of reactions involving nitrosation, esterification, and reaction with benzylhydrazine or hydrazine followed by reduction.
Q: What are the storage requirements for Isocarboxazid?
A: Isocarboxazid should be stored in a freezer at -20°C to maintain its stability.
Company Name | Contact | Product Details |
---|---|---|
Alchem PharmtechInc | Tel: 8485655694 | N-Benzyl-5-methylisoxazole-3-carbohydrazide, Purity: 97%, Package: 1g, 10g, 100g, 1kg |
Alfa Chemistry | Tel: 1-5166625404 | Isocarboxazid |
Shaanxi Didu New Materials Co., Ltd. | Tel: 86-89586680, 86-13289823923 | Isocarboxazid, Purity: 99%, Package: 25KG/200L |
TargetMol Chemicals Inc. | Tel: 1-781-999-5354 | Isocarboxazid, Package: 10 mg, Remarks: Reagent for laboratory use only |
Shanghai Acmec Biochemical Technology Co., Ltd. | Tel: 18621343501 | Isocarboxazid, Purity: 98%, Package: 5mg |
This article was written by bob and published on 2024-08-02 04:44:39. Original article, reproduction is prohibited. The content is for entertainment purposes only and should not be taken as fact.
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