Tetrahydropalmatine (CAS 2934-97-6) Suppliers and Product Information

Tetrahydropalmatine is a white to pale yellow solid compound. It has a melting point of 155°C and a boiling point of 482.9±45.0°C at 760 mmHg. The predicted density is 1.23±0.1 g/cm³. It is slightly soluble in chloroform and methanol.

Tetrahydropalmatine is an active component isolated from the Chinese herb Corydalis. It possesses ***gesic and hypnotic properties, and can induce hypotension and bradycardia in rats through the antagonism of striatal dopamine D2 receptors. It is used in research and has potential therapeutic applications.

What is Tetrahydropalmatine?

Tetrahydropalmatine is an alkaloid compound extracted from Corydalis plants. It has ***gesic, sedative, and hypnotic properties. It acts as a dopamine antagonist and has been studied for its potential in treating pain, anxiety, and addiction.

How is Tetrahydropalmatine prepared?

Tetrahydropalmatine can be prepared from the total bases of tetrahydroxy berberine. The process involves ring-opening of berberine hydrochloride, followed by methylation to form palmatine hydrochloride, which is then reduced to obtain tetrahydropalmatine.

What are the uses of Tetrahydropalmatine?

Tetrahydropalmatine has several potential uses: - As an ***gesic for pain relief - As a sedative and hypnotic agent - In research studying dopamine receptors - Potential therapeutic applications in treating anxiety and addiction It's important to note that while it has been used in traditional medicine, more research is needed to fully establish its efficacy and safety for clinical use.