Human Menopausal Gonadotrophin (HMG) CAS 61489-71-2 Suppliers and Product Information

**Synonyms:** Menopausal Gonadotrophin Human Urine, Menotropin, hMG, Fuji, Humegon 100, Lepori, Menogon, Menogon HP, Menopur

**Storage Temperature:** 2-8°C

**Description:** Human Menopausal Gonadotrophin (HMG), also known as Menotropins, is a combination of FSH and LH extracted from the urine of postmenopausal women at a ratio of 1:1. It is administered by intramuscular or subcutaneous injection for the treatment of infertility in women or men.

**Uses:** - Gonad stimulating - Treatment of anovulatory women with gonadotropin deficiency - Stimulation of spermatogenesis in men with hypogonadism - In vitro fertilization (IVF) programs

**Mechanism of Action:** HMG interacts with G protein-coupled receptors, activating adenylyl cyclase. It promotes follicle maturation, stimulates ovulation, and accelerates the development of corpus luteum.

**Side Effects:** Headache, mild stomach pain, bloating, redness or pain at the injection site, breast tenderness, dizziness. Serious side effects may include vaginal bleeding and flu-like symptoms.

Frequently Asked Questions about Human Menopausal Gonadotrophin (HMG)

Q: What is the main use of Human Menopausal Gonadotrophin? A: HMG is primarily used for the treatment of infertility in both women and men. It stimulates ovulation in women with anovulation due to hormonal imbalances and promotes spermatogenesis in men with hypogonadism.

Q: How is HMG administered? A: HMG is typically administered through intramuscular or subcutaneous injections. The dosage and duration of treatment are determined by a healthcare professional based on individual patient needs.

Q: Are there any precautions to consider when using HMG? A: Yes, HMG should be used under close medical supervision. Patients should be monitored for ovarian hyperstimulation syndrome, multiple pregnancies, and other potential complications. It's important to follow the prescribed dosage and schedule carefully.

Q: Can HMG be used in IVF treatments? A: Yes, HMG is commonly used in IVF programs to stimulate the development of multiple follicles, which increases the chances of successful egg retrieval and fertilization.