Property | Value |
---|---|
Chemical Name | Cefuroxime 1-acetoxyethyl ester |
CAS Number | 64544-07-6 |
Molecular Formula | C20H22N4O10S |
Molecular Weight | 510.47 g/mol |
Appearance | White or almost white powder |
Melting Point | 175-180°C |
Solubility | Soluble in DMSO (1mg/mL) |
Storage Temperature | -20°C |
Cefuroxime 1-acetoxyethyl ester is an oral prodrug form of cefuroxime, a second-generation cephalosporin antibiotic. It is used to treat various bacterial infections, including respiratory tract infections, urinary tract infections, and skin infections. The compound is converted to the active form, cefuroxime, by esterases in the body after oral administration.
Q: What is the mechanism of action of cefuroxime?
A: Cefuroxime, like other cephalosporins, works by binding to penicillin-binding proteins (PBPs) in bacterial cell walls. This inhibits the final step of peptidoglycan synthesis, preventing proper cell wall formation and leading to bacterial cell death.
Q: How is cefuroxime axetil absorbed in the body?
A: After oral administration, cefuroxime axetil is converted to the active compound cefuroxime by esterases in the mucosal cells of the gastrointestinal tract. The active cefuroxime is then released into systemic circulation. Absorption is enhanced when taken with food, increasing by up to 52% compared to fasting conditions.
Q: What are some common uses of cefuroxime axetil?
A: Cefuroxime axetil is commonly used to treat upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, gonorrhea, and early Lyme disease.
Company Name | Contact | Product Details |
---|---|---|
Hebei Mojin Biotechnology Co., Ltd. | 86 13288715578 | Purity: 99%, Package: 25KG |
Wuhan Fortuna Chemical Co., Ltd. | 86 027 59207850 | Purity: 745-875ug/mg (USP), Package: 1kg, 25kg, 1000kg |
Shaanxi TNJONE Pharmaceutical Co., Ltd. | 8618740459177 | Purity: 99%, Package: 1kg |
Henan Tianfu Chemical Co Ltd. | 86 0371 55170693, 86 19937530512 | Purity: 99%, Package: 25KG, 5KG, 1KG |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | Purity: 98%, Package: g, Kg |
This article was written by bob and published on 2024-08-01 01:19:22. Original article, reproduction is prohibited. The content is for entertainment purposes only and should not be taken as fact.
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