Property | Information |
---|---|
Chemical Name | Naphazoline hydrochloride |
CAS Number | 550-99-2 |
Molecular Formula | C14H14N2·HCl |
Molecular Weight | 246.74 |
Appearance | White crystalline powder |
Melting Point | 254-260°C |
Solubility | Freely soluble in water, soluble in ethanol (96%) |
pKa | 10.35 ± 0.02 (25°C), 10.13 ± 0.02 (35°C), 9.92 ± 0.03 (45°C) |
pH | 4.0-6.0 (5% solution) |
Water Solubility | 170 g/L (20°C) |
Naphazoline hydrochloride is an imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive properties. It is commonly used as a vasoconstrictor in otorhinolaryngology and ophthalmology. The compound acts as an adrenomimetic drug, causing strong contraction of blood vessels and elevation of blood pressure. It also has inhibitory effects on the central nervous system and can provide anti-inflammatory and ***gesic effects in local inflammatory lesions.
Uses: Treatment of colds, acute and chronic rhinitis, allergic conjunctivitis, allergic and inflammatory nasal congestion. It is typically used in eye drops and nasal sprays.
Cautions: Long-term local use can lead to reduced blood flow in the medication area. It should not be taken orally. Excessive use or high concentrations can cause poisoning, especially in children. Use with caution in patients with hypertension or hyperthyroidism. Contraindicated in patients with atrophic rhinitis.
Q: What are the main uses of Naphazoline hydrochloride?
A: Naphazoline hydrochloride is primarily used as a vasoconstrictor in eye drops and nasal sprays. It is used to treat conditions such as colds, acute and chronic rhinitis, allergic conjunctivitis, and inflammatory nasal congestion.
Q: What are the side effects of Naphazoline hydrochloride?
A: Side effects can include reduced blood flow in the medication area with long-term use, potential for poisoning with excessive use or high concentrations, and it may cause issues for patients with hypertension or hyperthyroidism. It should be used with caution, especially in children.
Q: How is Naphazoline hydrochloride typically administered?
A: Naphazoline hydrochloride is typically administered topically as eye drops or nasal sprays. It should not be taken orally. The interval between doses is preferably not less than 4 to 6 hours.
Q: Can Naphazoline hydrochloride be used by everyone?
A: No, Naphazoline hydrochloride should be used with caution in certain groups. It is contraindicated for patients with atrophic rhinitis. Infants, patients with hypertension, and those with hyperthyroidism should use it cautiously. Always consult a healthcare professional before use.
Company Name | Contact | Product Details |
---|---|---|
Hebei Mojin Biotechnology Co., Ltd. | Tel: 86 13288715578 | Purity: 99%, Package: 25KG |
Hebei Yanxi Chemical Co., Ltd. | Tel: 86 17531190177 | Purity: 99%, Package: 1kg (20USD), 100kg (10USD), 1000kg (1USD) |
Hebei Duling International Trade Co., LTD | Tel: 8617333973358 | Purity: 99%, Package: 1kg (60.00 USD) |
Henan Bao Enluo International Trade Co., LTD | Tel: 86 17331933971 | Purity: 99.9%, Package: 1kg (50USD) |
Anhui Ruihan Technology Co., Ltd. | Tel: 8617756083858 | Purity: 99%, Package: 1kg (30USD) |
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