Nonactin (CAS 6833-84-7) Suppliers and Product Information

Nonactin is a monovalent cation ionophore with high selectivity for NH4 and K . It is used as an antibiotic and in research applications. Nonactin is produced by various Streptomyces species and belongs to the macrotetrolide family of compounds.

Frequently Asked Questions about Nonactin

Q: What is the primary use of Nonactin?

A: Nonactin is primarily used as a monovalent cation ionophore in research applications, particularly for its selectivity towards ammonium (NH4 ) and potassium (K ) ions. It is also used as an antibiotic and has potential applications in cancer research due to its ability to inhibit P-glycoprotein-mediated efflux of chemotherapeutic agents in multiple drug-resistant cancer cells.

Q: How should Nonactin be stored?

A: Nonactin should be stored at -20°C. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Q: Is Nonactin safe to handle?

A: Nonactin should be handled with care. It is classified as an irritant (Xi) and has specific safety phrases (S22, S24, S25). It is not for use in humans or for diagnostic/therapeutic purposes. Always refer to the material safety data sheet (MSDS) and use appropriate personal protective equipment when handling.