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Trimetazidine Suppliers and Product Information

  • bobbob
  • API
  • 2024-07-23 12:51:25
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PropertyValue
Product NameTrimetazidine
CAS Number5011-34-7
Molecular FormulaC14H22N2O3
Molecular Weight266.34
EINECS225-690-2
Boiling Point200-205°C
Density1.092 ± 0.06 g/cm3
Predicted Vapor Pressure0.003Pa at 25°C
StorageHygroscopic, Refrigerator, Under inert atmosphere
SolubilitySlightly soluble in Chloroform and Methanol
FormSolid
pKa9.07 ± 0.10
ColorColorless to Pale Yellow Gel
LogP1.143 at 25°C and pH 6

Trimetazidine is a piperazine derivative used for the symptomatic treatment of stable angina pectoris. It acts as an anti-angina drug by antagonizing ***, norepinephrine, and vasopressin. The drug relaxes vascular smooth muscle, reduces vascular resistance, increases coronary and peripheral blood flow, promotes myocardial metabolism, and reduces myocardial oxygen consumption.

Frequently Asked Questions about Trimetazidine

Q: What is the main use of Trimetazidine?

2Trimetazidine Suppliers and Product Information

A: Trimetazidine is primarily used for the treatment of coronary insufficiency, angina pectoris, and old myocardial infarction. It can also be used in combination with digitalis in patients with severe heart failure.

Q: How does Trimetazidine work?

A: Trimetazidine works by providing direct cell protection to the heart. It conserves energy metabolism in ischemic oxygen cells, maintains intracellular environment stability, ensures proper ion pump function, reduces intracellular acidosis, and protects against cell damage caused by oxygen free radicals.

Q: What are the common side effects of Trimetazidine?

A: A few patients may experience gastrointestinal discomfort, nausea, and vomiting when taking Trimetazidine.

Q: Are there any precautions for using Trimetazidine?

A: Trimetazidine is contraindicated in patients with allergies and new myocardial infarction. Pregnant women and lactating mothers should use this drug with caution. For safety reasons, it's advisable to consult a healthcare professional before use.

Company NameContact InformationProduct Details
Henan Tianfu Chemical Co., Ltd.Tel: 86 0371 55170693, 86 19937530512Purity: 99%, Package: 25KG/5KG/1KG
CONIER CHEM AND PHARMA LIMITEDTel: 8618523575427Purity: ≥99%, Package: 1kg
Career Henan Chemical Co.Tel: 86 0371 86658258, 8613203830695Purity: 98%, Package: 1g (1USD)
Hefei TNJ Chemical Industry Co., Ltd.Tel: 0551-65418671Not specified
Xi'an MC Biotech Co., Ltd.Tel: 029-89275612, 8618991951683Purity: 98%, Package: 1G/10G/1KG/5KG/10KG