Sumatriptan (CAS 103628-46-2) Suppliers and Product Information

Sumatriptan is a serotonin 5-HT1 receptor agonist used for the acute treatment of migraine with or without aura in ***s. It is available in various formulations including oral tablets, subcutaneous injections, nasal sprays, and suppositories. Sumatriptan works by selectively binding to vascular 5-HT1 receptors, likely of the 5-HT1D family, to provide relief from migraine symptoms.

Frequently Asked Questions about Sumatriptan

Q: What is the primary use of Sumatriptan?

A: Sumatriptan is primarily used for the acute treatment of migraine headaches with or without aura in ***s.

Q: How does Sumatriptan work?

A: Sumatriptan works as a selective agonist for vascular 5-HT1 receptors, likely of the 5-HT1D family, to provide relief from migraine symptoms.

Q: What are the available formulations of Sumatriptan?

A: Sumatriptan is available in various formulations, including oral tablets, subcutaneous injections, nasal sprays, and suppositories.

Q: Are there any significant drug interactions with Sumatriptan?

A: Yes, Sumatriptan has potentially hazardous interactions with certain antidepressants, MAOIs, ergot alkaloids, and other serotonergic drugs. It is important to consult a healthcare professional for a complete list of drug interactions.

Q: How is Sumatriptan metabolized?

A: Sumatriptan is extensively metabolized in the liver, mainly by monoamine oxidase type A (MAO-A). It is primarily excreted in the urine as inactive metabolites, with a small portion appearing in the feces.