Puromycin Aminonucleoside (CAS 58-60-6) Suppliers and Product Information

Puromycin aminonucleoside is the nucleoside moiety of puromycin. It does not inhibit protein synthesis or induce apoptosis but acts as a glomerular epithelial cell toxin. It is used for producing animal models of nephropathy and puromycin aminonucleoside nephrosis. The compound is also a key intermediate in the synthesis of semi-synthetic ***ogues of puromycin and exhibits antitumor properties.

Frequently Asked Questions about Puromycin Aminonucleoside

Q: What is the main use of Puromycin Aminonucleoside?

A: Puromycin Aminonucleoside is primarily used as a tool for producing animal models of nephropathy and puromycin aminonucleoside nephrosis. It acts as a glomerular epithelial cell toxin and is useful in studying kidney-related conditions.

Q: How does Puromycin Aminonucleoside differ from Puromycin?

A: Puromycin Aminonucleoside is the nucleoside portion of puromycin. Unlike puromycin, it does not inhibit protein synthesis or induce apoptosis. It lacks the methoxyphenylalanyl moiety present in puromycin.

Q: What are the storage conditions for Puromycin Aminonucleoside?

A: Puromycin Aminonucleoside should be kept in a dark place, under an inert atmosphere, at a temperature between 2-8°C. Solutions in DMSO or distilled water can be stored at -20°C for up to 2 months.