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Alacepril (CAS 74258-86-9) Suppliers and Product Information

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  • 2024-08-04 16:21:46
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Product NameAlacepril
CAS Number74258-86-9
Molecular FormulaC20H26N2O5S
Molecular Weight406.5
IUPAC Name(3-(acetylthio)-2-methylpropanoyl)prolylphenylalanine
Melting Point155-156°C
AppearanceWhite to off-white solid

Alacepril is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of essential and renal hypertension. It has a longer duration of action compared to captopril and appears to be more active due to an added component of norepinephrine antagonism.

2Alacepril (CAS 74258-86-9) Suppliers and Product Information

Alacepril is classified as an active pharmaceutical ingredient. It acts as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and has a role in treating hypertension.

Frequently Asked Questions about Alacepril

Q: What is the main use of Alacepril?

A: Alacepril is primarily used as an antihypertensive medication for the treatment of essential and renal hypertension.

Q: How does Alacepril compare to other ACE inhibitors?

A: Compared to captopril, Alacepril is a weaker ACE inhibitor in vitro. However, clinically it has a longer duration of action and appears to be more active due to an added component of norepinephrine antagonism.

Q: What is the toxicity profile of Alacepril?

A: The LD50 for Alacepril in rats and mice is >5000 mg/kg orally, >3000 mg/kg subcutaneously, and 2000-3000 mg/kg intraperitoneally.

Q: Who was the original developer of Alacepril?

A: Alacepril was originally developed by Dainippon in Japan.

Company NameContactProduct Details
Hubei Jusheng Technology Co LtdTel: 18871490254Purity: ≥99%, Package: 5KG/1KG
CONIER CHEM AND PHARMA LIMITEDTel: 8618523575427Purity: ≥99%, Package: 1kg
Shaanxi Dideu Medichem Co., Ltd.Tel: 86 029-89586680, 86 18192503167Purity: 99.9%, Package: 25kgs/200kgs Drum, FDA/GMP/CEP Approved
Shijiazhuang Gantuo Biotechnology Co., Ltd.Tel: 8613373514458Purity: ≥99%, Package: 1KG, Price: 100USD
Hebei Lingding Biotechnology Co., Ltd.Tel: 86 18031140164, 86 19933155420Purity: ≥99%, Package: 1KG, Price: 15USD