Property | Value |
---|---|
Product Name | Alacepril |
CAS Number | 74258-86-9 |
Molecular Formula | C20H26N2O5S |
Molecular Weight | 406.5 |
IUPAC Name | (3-(acetylthio)-2-methylpropanoyl)prolylphenylalanine |
Melting Point | 155-156°C |
Appearance | White to off-white solid |
Alacepril is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of essential and renal hypertension. It has a longer duration of action compared to captopril and appears to be more active due to an added component of norepinephrine antagonism.
Alacepril is classified as an active pharmaceutical ingredient. It acts as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and has a role in treating hypertension.
Q: What is the main use of Alacepril?
A: Alacepril is primarily used as an antihypertensive medication for the treatment of essential and renal hypertension.
Q: How does Alacepril compare to other ACE inhibitors?
A: Compared to captopril, Alacepril is a weaker ACE inhibitor in vitro. However, clinically it has a longer duration of action and appears to be more active due to an added component of norepinephrine antagonism.
Q: What is the toxicity profile of Alacepril?
A: The LD50 for Alacepril in rats and mice is >5000 mg/kg orally, >3000 mg/kg subcutaneously, and 2000-3000 mg/kg intraperitoneally.
Q: Who was the original developer of Alacepril?
A: Alacepril was originally developed by Dainippon in Japan.
Company Name | Contact | Product Details |
---|---|---|
Hubei Jusheng Technology Co Ltd | Tel: 18871490254 | Purity: ≥99%, Package: 5KG/1KG |
CONIER CHEM AND PHARMA LIMITED | Tel: 8618523575427 | Purity: ≥99%, Package: 1kg |
Shaanxi Dideu Medichem Co., Ltd. | Tel: 86 029-89586680, 86 18192503167 | Purity: 99.9%, Package: 25kgs/200kgs Drum, FDA/GMP/CEP Approved |
Shijiazhuang Gantuo Biotechnology Co., Ltd. | Tel: 8613373514458 | Purity: ≥99%, Package: 1KG, Price: 100USD |
Hebei Lingding Biotechnology Co., Ltd. | Tel: 86 18031140164, 86 19933155420 | Purity: ≥99%, Package: 1KG, Price: 15USD |
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