Clindamycin (CAS 18323-44-9) Suppliers and Product Information

Clindamycin is a semi-synthetic antibiotic derived from lincomycin. It is effective against anaerobic bacteria and gram-positive cocci. Clindamycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It is used to treat various bacterial infections and is also available in topical formulations for acne treatment.

Frequently Asked Questions about Clindamycin

What is Clindamycin used for?

Clindamycin is used to treat various bacterial infections, including: - Anaerobic infections - Gram-positive bacterial infections - Skin and soft tissue infections - Respiratory tract infections - Intra-abdominal infections - Pelvic infections - Acne (topical formulation)

How does Clindamycin work?

Clindamycin inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome. This action prevents the formation of peptide bonds, ultimately leading to bacterial cell death or growth inhibition.

What are the common side effects of Clindamycin?

Common side effects of Clindamycin include: - Diarrhea (most common) - Nausea and vomiting - Abdominal pain - Skin rash - Elevated liver enzymes In rare cases, Clindamycin can cause a serious condition called Clostridioides difficile-associated diarrhea (CDAD).

Are there any drug interactions with Clindamycin?

Yes, Clindamycin may interact with other medications. Notable interactions include: - Erythromycin (antagonistic effect, should not be used concurrently) - Cyclosporine (may reduce cyclosporine levels) - Neuromuscular blocking agents (enhanced effect) Always consult with a healthcare professional before combining Clindamycin with other medications.