Fosfomycin Tromethamine (CAS 78964-85-9) Suppliers and Product Information

Fosfomycin Tromethamine is a broad-spectrum bactericidal antibiotic used primarily for the treatment of urinary tract infections. It inhibits bacterial cell wall synthesis by inactivating the enzyme UDP-N-acetylglucosamine enolpyruvyl transferase (MurA).

Frequently Asked Questions about Fosfomycin Tromethamine

Q: What is the main use of Fosfomycin Tromethamine?

A: Fosfomycin Tromethamine is primarily used as an antibiotic for the treatment of uncomplicated urinary tract infections.

Q: How does Fosfomycin Tromethamine work?

A: It works by inhibiting bacterial cell wall biosynthesis through the inactivation of the enzyme UDP-N-acetylglucosamine enolpyruvyl transferase (MurA).

Q: What is the advantage of the tromethamine salt form?

A: The tromethamine salt form greatly increases the water solubility of fosfomycin, allowing for oral administration.

Q: Is Fosfomycin Tromethamine effective against resistant bacteria?

A: Fosfomycin has shown efficacy against various bacteria, including some resistant strains. The frequency of resistant mutants in vitro studies has been low, and there appears to be little cross-resistance between fosfomycin and other antibacterials.