Cinepazide (CAS 23887-46-9) Suppliers and Product Information

Cinepazide is a vasodilator used primarily in China for treating cardiovascular, cerebrovascular, and peripheral vascular diseases. It acts as a potentiator of adenosine A2 receptors and has been characterized as a calcium channel blocker. The drug can relax smooth muscles of cerebral vessels, coronary arteries, and peripheral vessels, thereby improving blood circulation and brain metabolism.

Frequently Asked Questions

Q: What is the main use of Cinepazide?

A: Cinepazide is primarily used as a vasodilator for the treatment of cardiovascular, cerebrovascular, and peripheral vascular diseases.

Q: Is Cinepazide available worldwide?

A: Cinepazide is mainly used in China under the trade names Kelinao or Anjieli. It was previously marketed in Japan but was withdrawn in 1999.

Q: What are the mechanisms of action for Cinepazide?

A: Cinepazide acts as a potentiator of adenosine A2 receptors and has been characterized as a calcium channel blocker. It can relax smooth muscles of blood vessels, improve blood circulation, and enhance brain metabolism.

Q: Are there any known side effects of Cinepazide?

A: There have been reports of blood dyscrasias, including agranulocytosis and thrombocytopenia, associated with the use of Cinepazide. This led to its withdrawal in some countries and warnings being added to product information in others.