Fenoldopam (CAS 67227-56-9) Suppliers and Product Information

Fenoldopam is a selective dopamine D1 receptor agonist with diuretic and vasodilator properties. It is used as an antihypertensive agent. The compound appears as an off-white powder and is soluble in DMSO (>12.160 mg/mL). It has a predicted storage temperature of 2-8°C and a predicted density of 1.380±0.06 g/cm³.

Fenoldopam is primarily used in the treatment of severe hypertension and has been approved by regulatory agencies such as the FDA. It acts as a dopaminergic antagonist, vasodilator, alpha-adrenergic agonist, and dopamine agonist. The drug does not readily cross the blood-brain barrier, which limits its central nervous system effects.

Frequently Asked Questions about Fenoldopam

Q: What is the primary use of Fenoldopam?

A: Fenoldopam is primarily used as an antihypertensive agent for the treatment of severe hypertension. It acts as a selective dopamine D1 receptor agonist with vasodilator properties.

Q: How does Fenoldopam work?

A: Fenoldopam works by selectively stimulating dopamine D1 receptors, leading to vasodilation and increased renal blood flow. This mechanism helps to lower blood pressure and improve kidney function.

Q: What are the advantages of Fenoldopam over other antihypertensive medications?

A: Fenoldopam has a rapid onset of action and a short half-life, making it suitable for use in acute hypertensive situations. It also does not readily cross the blood-brain barrier, which may result in fewer central nervous system side effects compared to some other antihypertensive drugs.

Q: Are there any specific storage requirements for Fenoldopam?

A: Based on the product information, Fenoldopam has a predicted storage temperature of 2-8°C. It's important to follow the manufacturer's specific storage instructions to maintain the drug's stability and efficacy.