Cefonicid Sodium (CAS 61270-78-8) Suppliers and Product Information

Cefonicid sodium is a second-generation cephalosporin antibiotic with broad-spectrum antibacterial activity. It inhibits bacterial cell wall formation and is effective against various gram-positive and gram-negative bacteria, including Escherichia coli, Klebsiella, Citrobacter, Enterobacter, indole-negative Proteus, and Providencia. Its long serum half-life of approximately 4-5 hours allows for once-daily intravenous administration.

Frequently Asked Questions about Cefonicid Sodium

Q: What is the primary use of Cefonicid sodium?

A: Cefonicid sodium is primarily used as a broad-spectrum antibiotic for treating various bacterial infections, including urinary tract infections, lower respiratory tract infections, skin and skin structure infections, and bone and joint infections. It is also used in surgical prophylaxis.

Q: How does Cefonicid sodium work?

A: Cefonicid sodium works by interfering with bacterial cell wall biosynthesis, leading to the lysis of infectious organisms. It is resistant to β-lactamases produced by certain bacteria, making it effective against some antibiotic-resistant strains.

Q: What are the advantages of Cefonicid sodium over other antibiotics?

A: Cefonicid sodium has a longer serum half-life compared to other second-generation cephalosporins, allowing for once-daily administration. It also has a broad spectrum of activity and is effective against various gram-positive and gram-negative bacteria.

Q: Are there any precautions or side effects associated with Cefonicid sodium?

A: As with other antibiotics, Cefonicid sodium may cause side effects. In animal studies, high doses have been associated with testicular toxicity in rats. It's important to use this medication under proper medical supervision and follow prescribed dosages.