Manidipine (CAS 89226-50-6) Suppliers and Product Information

Manidipine is a calcium channel blocker of the dihydropyridine class. It is used clinically as an antihypertensive agent. Manidipine is a lipophilic, third-generation calcium antagonist that blocks L- and T-type calcium channels.

Manidipine inhibits voltage-dependent calcium inward currents in smooth muscle cells, causing systemic vasodilation. It has been shown to lower blood pressure in spontaneously hypertensive rats and inhibit left ventricular hypertrophy in rats induced by isoproterenol.

Frequently Asked Questions about Manidipine

Q: What is the primary use of Manidipine?

A: Manidipine is primarily used as an antihypertensive agent to treat high blood pressure. It works by blocking calcium channels in smooth muscle cells, causing vasodilation and lowering blood pressure.

Q: What type of calcium channel blocker is Manidipine?

A: Manidipine is a dihydropyridine-type calcium channel blocker. It is classified as a lipophilic, third-generation calcium antagonist that blocks both L-type and T-type calcium channels.

Q: How should Manidipine be stored?

A: Manidipine should be stored sealed in a dry environment at a temperature between 2-8°C (35.6-46.4°F).

Q: What is the molecular weight of Manidipine?

A: The molecular weight of Manidipine is 610.7 g/mol.