Azelastine (CAS 58581-89-8) Suppliers and Product Information

Azelastine is a potent, long-lasting histamine H1-receptor antagonist with additional anti-inflammatory properties. It is used in the treatment of allergic rhinitis and allergic conjunctivitis. Azelastine is available as a nasal spray and eye drops. In some countries, it is also used systemically for asthma and seasonal allergies.

Safety Information: Azelastine is poisonous by ingestion, subcutaneous, intravenous, and intraperitoneal routes. It may cause experimental reproductive effects. When heated to decomposition, it emits toxic fumes of NOx and Cl-.

Frequently Asked Questions about Azelastine

Q: What is the primary use of Azelastine?

A: Azelastine is primarily used as an antihistamine for treating allergic rhinitis (nasal allergies) and allergic conjunctivitis (eye allergies). It is available as a nasal spray and eye drops.

Q: How does Azelastine work?

A: Azelastine works as a histamine H1-receptor antagonist. It also has additional anti-inflammatory properties, including the ability to stabilize mast cells and prevent the release of inflammatory mediators like histamine, leukotrienes, and PGD2.

Q: Is Azelastine available for systemic use?

A: In some countries, particularly in Europe, Azelastine is available for systemic use in the treatment of asthma and seasonal allergies.

Q: What are the storage requirements for Azelastine?

A: Azelastine should be stored under refrigerated conditions, typically at 2-8°C.