Luliconazole (CAS 187164-19-8) Suppliers and Product Information

Luliconazole is a novel topical antifungal imidazole used for treating fungal infections such as athlete's foot, jock itch, and ringworm. It works by inhibiting ergosterol synthesis in fungal cell membranes, leading to fungal cell death. Luliconazole has shown superior efficacy compared to other antifungal agents like terbinafine, ketoconazole, and miconazole.

Frequently Asked Questions about Luliconazole

What is Luliconazole used for?

Luliconazole is primarily used to treat fungal skin infections such as athlete's foot, jock itch, and ringworm. It's also being developed for the treatment of onychomycosis (nail fungus).

How does Luliconazole work?

Luliconazole works by inhibiting the enzyme lanosterol 14α-demethylase, which is crucial for ergosterol synthesis in fungal cell membranes. This leads to changes in cell membrane permeability and ultimately results in fungal cell death.

What is the typical dosage form of Luliconazole?

Luliconazole is typically available as a 1% topical cream for skin infections. It's applied once daily for one to two weeks, depending on the type and severity of the infection.

Are there any side effects associated with Luliconazole?

Luliconazole is generally well-tolerated. However, some users may experience mild side effects such as itching, burning, or redness at the application site. If these symptoms persist or worsen, it's advisable to consult a healthcare professional.

How does Luliconazole compare to other antifungal medications?

Studies have shown that Luliconazole has broader spectrum antifungal activity and is more potent than many commonly used antifungal drugs like terbinafine, ketoconazole, and miconazole. It has particularly high efficacy against Trichophyton rubrum, a common cause of fungal skin infections.