Formoterol Fumarate (CAS 43229-80-7) Suppliers and Product Information

Formoterol fumarate is a potent, selective, and long-acting β2-adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It demonstrates 330-fold selectivity for β2 over β1 receptors and has a fast onset of action with prolonged duration.

Frequently Asked Questions

Q: What is the main use of Formoterol fumarate?

A: Formoterol fumarate is primarily used as a long-acting bronchodilator for the treatment of asthma and chronic obstructive pulmonary disease (COPD). It helps to relax and open the airways, making breathing easier for patients with these conditions.

Q: How does Formoterol fumarate work?

A: Formoterol fumarate works by selectively binding to β2-adrenergic receptors in bronchial smooth muscle. This stimulates intracellular adenyl cyclase, increasing the production of cyclic adenosine monophosphate (cAMP), which leads to muscle relaxation and bronchodilation.

Q: What are the advantages of Formoterol fumarate over other β2-agonists?

A: Formoterol fumarate has several advantages, including: 1. High potency (150-200 times more potent than isoprenaline) 2. Fast onset of action 3. Long duration of effect 4. High selectivity for β2 receptors (330-fold selectivity over β1 receptors) These properties make it an effective and long-lasting treatment for asthma and COPD.