Monensin Sodium Salt (CAS 22373-78-0) Suppliers and Product Information

Monensin sodium salt is a polyether ionophore antibiotic produced by Streptomyces cinnamonensis. It is used to treat bacterial, fungal, and parasitic infections, and has applications in research for studying ion transport across cell membranes.

Key properties and uses: - Blocks glycoprotein secretion - Inhibits HDL's ability to decrease cellular cholesterol esterification - Forms complexes with monovalent cations, especially sodium - Effective against Gram-positive bacteria, some fungi, and certain protozoa - Used in potentiometric and spectroscopic studies of alkali metal ion complexes - Prevents coccidiosis in poultry production

Frequently Asked Questions

Q: What is the mechanism of action of monensin sodium salt?

A: Monensin sodium salt acts as an ionophore, forming complexes with monovalent cations (especially sodium) and facilitating their transport across lipid membranes. This affects the pH and sodium-potassium balance of cells, leading to cell death in susceptible organisms.

Q: What are the main applications of monensin sodium salt?

A: Monensin sodium salt is used as an antibiotic against Gram-positive bacteria, fungi, and some parasites. It is also used in research to study ion transport and in the poultry industry to prevent coccidiosis. Additionally, it has applications in biochemical studies related to glycoprotein secretion and cholesterol metabolism.

Q: How should monensin sodium salt be stored?

A: Monensin sodium salt should be stored at 2-8°C. Solutions in DMSO can be stored at -20°C for up to 1 month.