Toltrazuril (CAS 69004-03-1) Suppliers and Product Information

Toltrazuril is an antiprotozoal agent widely used in veterinary applications to prevent and treat coccidial infections. It is effective against all intracellular development stages of coccidia, acting as a coccidiocidal agent. The drug is not commercially available in the United States but is used in other countries for various animal species, including swine, calves, lambs, dogs, cats, and horses.

Frequently Asked Questions about Toltrazuril

Q: What is the primary use of Toltrazuril?

A: Toltrazuril is primarily used as an antiprotozoal agent to prevent and treat coccidial infections in various animal species, including swine, calves, lambs, dogs, cats, and horses.

Q: How does Toltrazuril work?

A: Toltrazuril acts against all intracellular development stages of coccidia parasites, including merogony (asexual multiplication) and gamogony (sexual phase). It inhibits nuclear division of schizonts and microgamonts, as well as the wall-forming bodies of macrogamonts, effectively destroying all stages of the parasite.

Q: What are the benefits of using Toltrazuril?

A: Toltrazuril has demonstrated several benefits, including: - Preventing and reducing the severity of lesions - Stopping oocyst shedding - Improving growth rate - Improving feed conversion in treated animals

Q: Is Toltrazuril available in the United States?

A: Toltrazuril is not commercially available in the United States but is used in other countries for veterinary applications.

Q: What are the environmental concerns associated with Toltrazuril use?

A: The main metabolite of Toltrazuril, toltrazuril sulfone (ponazuril), is persistent in the environment with a half-life of about 1 year. It is mobile and can have adverse effects on plant growth and emergence. Repeated spreading of manure from treated animals may lead to accumulation in soil and potential leaching into groundwater.