Property | Information |
---|---|
Product Name | Hygromycin B |
CAS Number | 31282-04-9 |
Molecular Formula | C20H37N3O13 |
Molecular Weight | 527.52 |
Melting Point | 160-180°C |
Solubility | Miscible with water, methanol, buffer solution, and ethanol |
Form | Powder |
Color | Faintly brown to brown |
Storage Temperature | 2-8°C |
Hygromycin B is an aminoglycoside antibiotic produced by Streptomyces hygroscopicus. It inhibits protein synthesis in both prokaryotic and eukaryotic cells by binding to ribosomal subunits. It is commonly used in molecular and cell biology applications for selecting transformed cells expressing hygromycin resistance genes.
Q: What is the primary use of Hygromycin B?
A: Hygromycin B is primarily used as a selective antibiotic in molecular biology for selecting transformed cells that express hygromycin resistance genes. It is also used as an antibacterial, antifungal, and anthelmintic agent.
Q: How does Hygromycin B work?
A: Hygromycin B inhibits protein synthesis by binding to ribosomal subunits, interfering with translocation, and causing mistranslation. It is effective against both prokaryotic (70S) and eukaryotic (80S) ribosomes.
Q: What is the recommended storage condition for Hygromycin B?
A: Hygromycin B should be stored at 2-8°C. Stock solutions should also be kept at this temperature range.
Q: Is Hygromycin B water-soluble?
A: Yes, Hygromycin B is water-soluble. It is also miscible with methanol, buffer solutions, and ethanol.
Company Name | Contact | Product Details |
---|---|---|
Henan Fengda Chemical Co., Ltd. | 86 371 86557731, 86 13613820652 | Purity: 99%, Package: 1KG $8, 25KG $5, 100KG $0.8 |
Shanghai Affida new material science and technology center | 15081010295 | Purity: 99%, Package: 1KG, 25KG, 50KG (Prices not provided) |
Apeloa production Co Limited | 8619933239880 | Purity: 98%, Package: 1g $1.00 |
Henan Tianfu Chemical Co Ltd | 86 0371 55170693, 86 19937530512 | Purity: 99%, Package: 25KG, 5KG, 1KG (Prices not provided) |
Career Henan Chemical Co | 86 0371 86658258, 8613203830695 | Purity: 99%, Package: 1KG $1 |
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