Property | Value |
---|---|
Product Name | Methimazole |
CAS Number | 60-56-0 |
Molecular Formula | C4H6N2S |
Molecular Weight | 114.17 |
Melting Point | 144-147°C |
Boiling Point | 280°C |
Appearance | White to slightly cream or pale buff crystalline powder |
Solubility | Soluble in water, alcohol, chloroform; slightly soluble in ether, benzene |
pKa | 12.37 |
Methimazole is an antithyroid medication used in the treatment of hyperthyroidism and Graves' disease. It works by inhibiting the incorporation of iodine into tyrosyl residues of thyroglobulin, thus lowering thyroid hormone levels. It is also known as thiamazole and acts as a thyroid hormone antagonist.
Uses: - Treatment of hyperthyroidism - Inhibition of thyroid hormone synthesis - Intermediate in pharmaceutical production - Research chemical in biochemistry and endocrinology studies
Safety Information: - Hazard Codes: Xn - Risk Statements: 43, 62, 63, 22 - Safety Statements: 26, 27, 36, 45, 36/37 - WGK Germany: 3 - Proper handling and protective equipment are required when working with this compound.
Q: What is the primary use of Methimazole? A: Methimazole is primarily used for the treatment of hyperthyroidism by inhibiting the production of thyroid hormones.
Q: How does Methimazole work? A: Methimazole works by inhibiting the incorporation of iodine into tyrosyl residues of thyroglobulin, thus lowering thyroid hormone levels in the body.
Q: What are the common side effects of Methimazole? A: Common side effects may include hematologic reactions (such as neutropenia), skin reactions (rash, itching), and rarely, liver damage. Regular blood tests and liver function monitoring are recommended during treatment.
Q: Is Methimazole used in veterinary medicine? A: Yes, Methimazole is considered the drug of choice for treating feline hyperthyroidism. It has also shown potential in preventing cisplatin-induced nephrotoxicity in dogs.
Q: How should Methimazole be stored? A: Methimazole should be stored in well-closed, light-resistant containers at a temperature of 2-8°C.
Company Name | Contact | Product Details |
---|---|---|
Henan Suikang Pharmaceutical Co., Ltd. | Tel: 86 18239973690 | Purity: 99.0%, Package: 1kg, 25kg |
Henan Tianfu Chemical Co., Ltd. | Tel: 86 0371 55170693, 86 19937530512 | Purity: 99%, Package: 25KG, 5KG, 1KG |
Shanghai Time Chemicals CO., Ltd. | Tel: 86 021 57951555, 8617317452075 | Product Name: 2-Mercapto-1-methylimidazole |
Nanjing ChemLin Chemical Industry Co., Ltd. | Tel: 025-83697070 | Purity: 98%, Package: g, Kg |
ATK CHEMICAL COMPANY LIMITED | Tel: 86 21 51877795 | Purity: 98% HPLC, Package: 5G, 10G, 25G, 50G, 100G, 250G, 1KG |
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