5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole (CAS 124750-53-4) Suppliers and Product Information

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole is an intermediate used in the preparation of labeled Candesartan and in the synthesis of antimicrobial agents. It is also known as an impurity in Olmesartan Medoxomil synthesis. The compound is typically stored at room temperature under an inert atmosphere.

Frequently Asked Questions

Q: What is the primary use of 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole?

A: This compound is primarily used as an intermediate in the synthesis of pharmaceutical products, particularly in the preparation of labeled Candesartan and antimicrobial agents. It is also known as an impurity in the synthesis of Olmesartan Medoxomil.

Q: How is 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole synthesized?

A: The compound is synthesized by reacting trityl chloride with 2-(tetrazol-5-yl)-4'-methyl-[1,1'-biphenyl] in acetone, using sodium hydroxide solution. The reaction is typically carried out at 40°C and monitored by TLC until completion.

Q: What are the storage recommendations for this compound?

A: It is recommended to store 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole at room temperature under an inert atmosphere to maintain its stability.