Lorcainide (CAS 59729-31-6) Suppliers and Product Information

Lorcainide is a cardiac depressant and anti-arrhythmic agent. It was originally marketed under the brand names Remivox, Lopantrol, and Lorivox. The compound is an acetamide derivative and acts as a Class IC antiarrhythmic drug.

**Synonyms:** - N-(4-chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-4-yl)acetamide - N-(4-Chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]benzeneacetamide - R-15889 - Ro-13-1042

**Toxicity:** LD50 in male mice, male and female rats (mg/kg): 18.8, 19.3, 18.6 (i.v.); 483, 395, 435 (orally) (Barton Marsboom)

**Side Effects:** Side effects include insomnia and gastrointestinal disturbances.

Frequently Asked Questions about Lorcainide

**Q: What is the main use of Lorcainide?**

A: Lorcainide is primarily used as a cardiac depressant and anti-arrhythmic agent. It belongs to the Class IC antiarrhythmic drugs and is used to treat certain types of abnormal heart rhythms.

**Q: How is Lorcainide synthesized?**

A: Lorcainide is synthesized through a process involving the reaction of N-(4-chlorophenyl)-N-(4-piperidinyl)benzeneacetamide with 2-bromopropane in the presence of sodium carbonate and potassium iodide. The reaction is carried out in butanol, followed by the preparation of the hydrochloride salt.

**Q: What are the storage recommendations for Lorcainide?**

A: While specific storage recommendations are not provided in the search results, most pharmaceutical compounds should be stored in a cool, dry place, protected from light and moisture. For precise storage conditions, consult the manufacturer's guidelines or a material safety data sheet (MSDS).