Property | Value |
---|---|
Product Name | Indobufen |
CAS Number | 63610-08-2 |
Molecular Formula | C18H17NO3 |
Molecular Weight | 295.34 |
Melting Point | 182-184°C |
Boiling Point | 518.1±50.0°C |
Predicted Density | 1.275±0.06 g/cm³ |
Storage | Keep in dark place, sealed, dry, room temperature |
Solubility | Slightly soluble in DMSO and Methanol |
Form | Solid |
pKa | 4.39±0.10 |
Predicted Color | White |
Indobufen is a platelet aggregation inhibitor related to the anti-inflammatory agent indoprofen. It has shown clinical efficacy in peripheral artery disease, prevention of deep vein thrombosis after myocardial infarction, and in blocking exercise-induced increase in platelet aggregation in angina patients. It is a reversible but very potent inhibitor of platelet COX-1 activity.
Q: What is the primary use of Indobufen?
A: Indobufen is primarily used as a platelet aggregation inhibitor and anticoagulant drug. It has anti-inflammatory and ***gesic effects and is used as an antithrombotic agent.
Q: What is the recommended dosage for Indobufen?
A: For the secondary prevention of thromboembolic events, 100 or 200 mg of indobufen twice daily is as effective as warfarin or aspirin in patients with or without atrial fibrillation.
Q: Is Indobufen available worldwide?
A: Currently, indobufen is only available for routine clinical use in Europe.
Q: What are some alternative names for Indobufen?
A: Some synonyms for Indobufen include 1-Oxo-2-(p-(α-ethyl-carboxymethyl)phenyl)isoindoline, 2-(p-1-Oxo-2-isoindolinyl)phenyl butyric acid, and K-2930.
Company Name | Contact Information | Product Details |
---|---|---|
Huadong Medicine Xi'an Bodyguard Pharmaceutical Co., Ltd. | Tel: 86 029 86185165, 8618629664246 | Purity: ≥99%, Package: 5KG, 1KG, 10KG, 25KG, Remarks: GMP/DMF |
Shandong Risen Sun Pharmaceutical Co., Ltd. | Tel: 86 15552509998, 86 15621883869 | Purity: 99% (HPLC), Package: 5KG, 1KG |
Beijing Hope Pharmaceutical Co., Ltd. | Tel: 86 010 67886402, 8613611125266 | Purity: ≥98%, Package: 10g, 100g, 200kg, 500kg |
Changzhou Rokechem Technology Co., Ltd. | Tel: 18758118018 | Purity: 99% (USP/EP/CP), Package: 1Kg, 5Kg, 25Kg |
Henan Bao Enluo International Trade Co., LTD | Tel: 86 17331933971 | Purity: 99.99%, Package: 1kg (20USD) |
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