Property | Value |
---|---|
Chemical Name | Ethynodiol diacetate |
CAS Number | 297-76-7 |
Molecular Formula | C24H32O4 |
Molecular Weight | 384.51 |
Melting Point | 126-127°C |
Boiling Point | 431.17°C (rough estimate) |
Appearance | White solid |
Solubility | Slightly soluble in chloroform and DMSO |
Water Solubility | 1.4mg/L (25°, 186°C) |
Ethynodiol diacetate is a synthetic progestogen used as a hormonal contraceptive. It is a steroid ester and a terminal acetylenic compound with roles as an estrogen receptor modulator and a contraceptive drug. It is also known as 17α-ethynyl-19-nor***-4-ene-3β,17β-diol diacetate.
The compound acts as a prodrug of norethindrone, requiring hydrolysis of both esters and oxidation of the C3 alcohol to the ketone for full progestin activity. It has been shown to prevent osteoporosis development in ovariectomized rats and inhibit copulatory ovulation in rabbits.
Q: What is the primary use of Ethynodiol Diacetate?
A: Ethynodiol Diacetate is primarily used as a hormonal contraceptive (birth control).
Q: How does Ethynodiol Diacetate work in the body?
A: Ethynodiol Diacetate is a prodrug that is converted to norethindrone in the body. It works by modulating estrogen receptors and acting as a progestin, which helps prevent ovulation and pregnancy.
Q: Are there any safety concerns with Ethynodiol Diacetate?
A: Ethynodiol Diacetate is a suspected carcinogen and may cause reproductive effects. It can affect the menstrual cycle and has shown experimental reproductive effects. Mutation data has also been reported. As with any medication, it should be used under medical supervision.
Q: How is Ethynodiol Diacetate manufactured?
A: Ethynodiol Diacetate is synthesized by reacting 17α-ethynyl-19-nor***-4-ene-3β,17β-diol with acetic anhydride in the presence of pyridine. The reaction mixture is then processed through several steps including cooling, precipitation, filtration, and extraction.
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This article was written by bob and published on 2024-08-04 04:26:44. Original article, reproduction is prohibited. The content is for entertainment purposes only and should not be taken as fact.
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