4-Epioxytetracycline (CAS 14206-58-7) Suppliers and Product Information

4-Epioxytetracycline is a metabolite of oxytetracycline and a degradation product formed by epimerisation of the dimethylamino group at C4 in solution at neutral to acidic pH. It is used as a secondary reference standard in stability studies of oxytetracycline and to study the degradation pathway of tetracyclines. The compound has been found in swine manure compost and wastewater and is considered a pollutant.

Frequently Asked Questions

Q: What is the main use of 4-Epioxytetracycline?

A: 4-Epioxytetracycline is primarily used as a secondary reference standard in stability studies of oxytetracycline and to study the degradation pathways of tetracyclines. It is also important for monitoring oxytetracycline stability.

Q: How does 4-Epioxytetracycline differ from oxytetracycline in terms of antibiotic activity?

A: The epimerisation that forms 4-Epioxytetracycline is associated with a loss of antibiotic activity compared to oxytetracycline. While it can compete with oxytetracycline for penetration through cell membranes, it does not suppress protein synthesis like the parent compound.

Q: What are the environmental implications of 4-Epioxytetracycline?

A: 4-Epioxytetracycline has been found in swine manure compost and wastewater, and is considered an environmental pollutant. Its presence in the environment may contribute to concerns about antibiotic resistance and ecological impacts.