Rosaprostol (CAS 56695-65-9) Supplier Information and Product Details

Rosaprostol is an antisecretory and cytoprotective prostaglandin ***og used in the treatment of gastric and duodenal ulcers. It is considerably less potent than enprostil or misoprostol and is reported to lack the typical gastrointestinal and cardiovascular side effects of PGE derivatives. Rosaprostol acts on the mucosal barrier in the stomach, preventing a drop in pH, and has been found to antagonize gastric acid output induced by NSAID administration.

Frequently Asked Questions about Rosaprostol

Q: What is Rosaprostol used for?

A: Rosaprostol is an antiulcer drug used in the treatment of gastric and duodenal ulcers. It exhibits gastric antisecretory activity and cytoprotective action.

Q: How does Rosaprostol work?

A: Rosaprostol acts on the mucosal barrier in the stomach, preventing a drop in pH. It antagonizes gastric acid output induced by NSAID administration and helps prevent and treat digestive disorders resulting from NSAID use.

Q: Are there any side effects associated with Rosaprostol?

A: Rosaprostol is reported to lack the typical gastrointestinal and cardiovascular side effects of PGE derivatives. It is generally well-tolerated.

Q: How is Rosaprostol synthesized?

A: Rosaprostol can be synthesized from enantiomerically pure stereoisomers. For example, the conversion of ( )-3 into rosaprostol stereoisomer (-)-1a can be accomplished in four steps with a 56% overall yield.